Active Ingredient: Epoprostenol
Epoprostenol is indicated for use in haemodialysis in emergency situations when use of heparin carries a high risk of causing or exacerbating bleeding or when heparin is otherwise contraindicated.
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
4 - 4 ng per kg of body weight
From 4 To 4 ng per kg of body weight once every day
Epoprostenol is suitable for continuous infusion only, either intravascularly or into the blood supplying the dialyser.
The following schedule of infusion has been found effective in adults:
Prior to dialysis: 4 ng/kg/min intravenously for 15 mins
During dialysis: 4 ng/kg/min into the arterial inlet of the dialyser
The infusion should be stopped at the end of dialysis.
The recommended dose for renal dialysis should be exceeded only with careful monitoring of patient blood pressure.
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