Epoprostenol

Chemical formula: C₂₀H₃₂O₅  Molecular mass: 352.465 g/mol  PubChem compound: 5280427

Active ingredient description

Epoprostenol sodium, the monosodium salt of epoprostenol, a naturally occurring prostaglandin produced by the intima of blood vessels. Epoprostenol is the most potent inhibitor of platelet aggregation known. It is also a potent vasodilator.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B01AC09 Epoprostenol B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AC Platelet aggregation inhibitors excl. heparin
Discover more medicines within B01AC09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VELETRI Powder for solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 35121-78-9
DrugBank Drug: DB01240
KEGG Drug: D00106
PubChem Compound: 5280427
RxNorm Ingredient: 8814
SNOMED-CT Concept: 372513003
Epoprostenol (substance)
UNII Identifier: DCR9Z582X0
EPOPROSTENOL

Medicines

Epoprostenol is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Canada (CA)

Estonia (EE)

  • FLOLAN as EPOPROSTENOL SODIUM

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

  • FLOLAN as EPOPROSTENOL SODIUM

Japan (JP)

  • FLOLAN as EPOPROSTENOL SODIUM

Malta (MT)

  • FLOLAN as EPOPROSTENOL SODIUM

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Singapore (SG)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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