Active Ingredient: Pegaptanib
Pegaptanib is indicated for the treatment of neovascular (wet) age-related macular degeneration (AMD) in adults.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intravitreal, 0.3 milligrams pegaptanib, once every 42 days.
The patient’s medical history for hypersensitivity reactions should be carefully evaluated prior to performing the intravitreal procedure.
The recommended dose is 0.3 mg pegaptanib, equivalent to 90 microliters, administered once every six weeks (9 injections per year) by intravitreal injection into the affected eye.
Following the injection, transient increases in intraocular pressure were seen in pegaptanib treated patients. Therefore, the perfusion of the optic nerve head and intraocular pressure should be monitored. Moreover patients should be closely monitored for vitreous haemorrhage and endophthalmitis in the two weeks following the injection. Patients should be instructed to report any symptoms suggestive of these conditions without delay.
After 2 consecutive injections of pegaptanib, if a patient does not demonstrate a treatment benefit (loss of less than 15 letters of visual acuity) at the 12-week visit, consideration should be given to stopping or withholding pegaptanib therapy.
For intravitreal injection use only.
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