Herpes labialis

Active Ingredient: Valaciclovir

Indication for Valaciclovir

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

4 g in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

4 - 4 g

Dosage regimen

From 2 To 2 g 2 time(s) per day every day for 1 day(s)

Detailed description

For herpes labialis (cold sores), valaciclovir 2,000 mg twice daily for one day is effective treatment in adults and adolescents. The second dose should be taken about 12 h (no sooner than 6 h) after the first dose. This dose should be reduced according to creatinine clearance. When using this dosing regimen, treatment should not exceed one day, since this has been shown not to provide additional clinical benefit. Therapy should be initiated at the earliest symptom of a cold sore (e.g. tingling, itching or burning).

Dosage considerations

It can be taken with or without food.

Active ingredient

Valaciclovir

Valaciclovir, an antiviral, is the L-valine ester of aciclovir. Valaciclovir is rapidly and almost completely converted in man to aciclovir and valine. Aciclovir is a specific inhibitor of the herpes viruses with in vitro activity against herpes simplex viruses (HSV) type 1 and type 2, varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and human herpes virus 6 (HHV-6).

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