Valaciclovir

Chemical formula: C₁₃H₂₀N₆O₄  Molecular mass: 324.336 g/mol  PubChem compound: 60773

Active ingredient description

Valaciclovir, an antiviral, is the L-valine ester of aciclovir. Valaciclovir is rapidly and almost completely converted in man to aciclovir and valine. Aciclovir is a specific inhibitor of the herpes viruses with in vitro activity against herpes simplex viruses (HSV) type 1 and type 2, varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and human herpes virus 6 (HHV-6).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
J05AB11 Valaciclovir J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
Discover more medicines within J05AB11

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 VALTREX Film-coated tablet MPI, US: SPL/PLR FDA, National Drug Code (US)
 VALACICLOVIR Film-coated tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 124832-26-4
DrugBank Drug: DB00577
KEGG Drug: D00398
PubChem Compound: 60773
RxNorm Ingredient: 73645
SNOMED-CT Concept: 96098007
Valaciclovir (substance)
UNII Identifier: MZ1IW7Q79D
VALACYCLOVIR

Medicines

Valaciclovir is an active ingredient of these brands:

Australia (AU)

Austria (AT)

  • VALDACIR as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE
  • VIROPEL as VALACYCLOVIR HYDROCHLORIDE

Brazil (BR)

  • DAZEK as VALACYCLOVIR HYDROCHLORIDE
  • HERPSTAL as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Canada (CA)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Cyprus (CY)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Ecuador (EC)

Estonia (EE)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Finland (FI)

  • FLUSHNIL as VALACYCLOVIR HYDROCHLORIDE
  • VALAVIR as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

France (FR)

  • ZELITREX as VALACYCLOVIR HYDROCHLORIDE

Hong Kong (HK)

  • VALAJUB as VALACYCLOVIR HYDROCHLORIDE
  • VALTRA as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Ireland (IE)

Israel (IL)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Italy (IT)

  • TALAVIR as VALACYCLOVIR HYDROCHLORIDE
  • ZELITREX as VALACYCLOVIR HYDROCHLORIDE

Japan (JP)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Lithuania (LT)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Mexico (MX)

Netherlands (NL)

  • ZELITREX as VALACYCLOVIR HYDROCHLORIDE

New Zealand (NZ)

Nigeria (NG)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Poland (PL)

  • VACICLOR as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Romania (RO)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Singapore (SG)

  • VACICLOR as VALACYCLOVIR HYDROCHLORIDE
  • VALOVIR as VALACYCLOVIR HYDROCHLORIDE
  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

United States (US)

  • VALTREX as VALACYCLOVIR HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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