Active Ingredient: Fluvastatin
Treatment of adults with primary hypercholesterolaemia or mixed dyslipidaemia, as an adjunct to diet, when response to diet and other non-pharmacological treatments (e.g. exercise, weight reduction) are inadequate.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
20 - 80 mg
From 10 To 40 mg 2 time(s) per day every day
Prior to initiating treatment with fluvastatin, patients should be placed on a standard cholesterol-lowering diet, which should be continued during treatment.
Starting and maintenance doses should be individualized according to the baseline LDL-C levels and the treatment goal to be accomplished.
The recommended dosing range is 20 to 80 mg/day. For patients requiring LDL-C reduction to a goal of <25% a starting dose of 20 mg may be used as one capsule in the evening. For patients requiring LDL-C reduction to a goal of ≥25%, the recommended starting dose is 40 mg as one capsule in the evening. The dose may be up-titrated to 80 mg daily, administered as a single dose (one fluvastatin 80 mg prolonged-release tablet) at any time of the day or as one 40 mg capsule given twice daily (one in the morning and one in the evening).
The maximum lipid-lowering effect with a given dose is achieved within 4 weeks. Dose adjustments should be made at intervals of 4 weeks or more.
It can be taken with or without meals and should be swallowed as whole with a glass of water.
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