Angina pectoris

Active Ingredient: Diltiazem

Indication for Diltiazem

Population group: only adults (18 - 65 years old)

Management of angina pectoris.

For this indication, competent medicine agencies globally authorize below treatments:

180-360 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

180 - 360 mg

Dosage regimen

From 90 To 180 mg 2 time(s) per day every day

Detailed description

The usual initial dose is 90 mg twice daily. Dosage may be increased gradually to 120 mg twice daily, or 180 mg twice daily if required. Patients' responses may vary and dosage requirements can differ significantly between individual patients.

180-360 mg in 3 divided doses daily

Route of admnistration

Oral

Defined daily dose

180 - 360 mg

Dosage regimen

From 60 To 120 mg 3 time(s) per day every day

Detailed description

The usual dose is one tablet (60mg) three times daily. However, patient responses may vary and dosage requirements can differ significantly between individual patients. If necessary the divided dose may be increased to 360mg/day. Higher doses up to 480mg/day have been used with benefit in some patients especially in unstable angina. There is no evidence of any decrease in efficacy at these high doses.

Active ingredient

Diltiazem

Diltiazem is a calcium antagonist. It restricts the slow channel entry of calcium into the cell and so reduces the liberation of calcium from stores in the sarcoplasmic reticulum. This results in a reduction of the amount of available intracellular calcium reducing myocardial oxygen consumption.

Read more about Diltiazem

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