Active Ingredient: Amitriptyline
Amitriptyline is indicated for the treatment of major depressive disorder in adults.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
50 - 150 mg
From 25 To 75 mg 2 time(s) per day every day for 180 day(s)
Dosage should be initiated at a low level and increased gradually, noting carefully the clinical response and any evidence of intolerability.
Initially 25 mg 2 times daily (50 mg daily). If necessary, the dose can be increased by 25 mg every other day up to 150 mg daily divided into two doses.
The maintenance dose is the lowest effective dose.
The antidepressant effect usually sets in after 2-4 weeks. Treatment with antidepressants is symptomatic and must therefore be continued for an appropriate length of time usually up to 6 months after recovery in order to prevent relapse.
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