Recalcitrant dermatoses

Active Ingredient: Clobetasol propionate

Indication for Clobetasol propionate

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

It is indicated for use in steroid responsive dermatoses of the scalp such as recalcitrant dermatoses.

For this indication, competent medicine agencies globally authorize below treatments:

2 spreads in 2 divided doses daily

Route of admnistration

Cutaneous

Defined daily dose

2 - 2 {spreads}

Dosage regimen

From 1 To 1 {spreads} 2 time(s) per day every day

Detailed description

A small quantity of clobetasol should be applied to the scalp night and morning until improvement is noticeable. It may then be possible to sustain improvement by applying once a day, or less frequently.

Active ingredient

Clobetasol propionate

Clobetasol propionate, like other topical corticosteroids, has anti-inflammatory, antipruritic, and vasoconstrictive properties. Corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid.

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