Active Ingredient: Amiloride
Although amiloride Hydrochloride may be used alone, its principal indication is as concurrent therapy with thiazides or more potent diuretics to conserve potassium during periods of vigorous diuresis and during long term maintenance therapy. In hypertension, it is used as an adjunct to prolonged therapy with thiazides and similar agents to prevent potassium depletion.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
2.5 - 5 mg
From 2.5 To 5 mg once every day
Usually 2.5mg given once a day together with the usual antihypertensive dosage of the thiazide concurrently employed. If necessary, increase to 5mg given once a day or in divided doses.
The elderly are more susceptible to electrolyte imbalance, and are more likely to experience hyperkalaemia since renal reserve may be reduced. The dosage should be carefully adjusted according to renal function, blood electrolytes and diuretic response.
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