Herpetic encephalitis

Active Ingredient: Aciclovir

Indication for Aciclovir

Population group: only children (1 year - 12 years old)

Aciclovir is indicated for the treatment of herpes encephalitis.

For this indication, competent medicine agencies globally authorize below treatments:

20 mg/kg every 8 hours for 10 days

Route of admnistration

Intravenous

Defined daily dose

60 mg per kg of body weight

Dosage regimen

20 mg per kg of body weight 3 time(s) per day every day for 10 day(s)

Detailed description

20 mg/kg infused at a constant rate over 1 hour, every 8 hours for 10 days.

Dosage considerations

Must be administered by slow intravenous infusion over one hour.

500 mg per square metre body surface area

Route of admnistration

Intravenous

Defined daily dose

1,500 mg per m² of body surface area (BSA)

Dosage regimen

500 mg per m² of body surface area (BSA) 3 time(s) per day every day for 10 day(s)

Detailed description

In immunocompromised children with Varicella zoster infections or children with herpes encephalitis, aciclovir should be given in doses of 500 mg per square metre body surface area every 8 hours if renal function is not impaired.

Active ingredient

Aciclovir

Acyclovir is an antiviral agent with activity against herpes simplex virus and varicella-zoster virus. Acyclovir inhibits the DNA polymerase of the virus, preventing further proliferation.

Read more about Aciclovir

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