Chemical formula: C₈H₁₁N₅O₃ Molecular mass: 225.205 g/mol PubChem compound: 135398513
Acyclovir is an antiviral agent with activity against herpes simplex virus and varicella-zoster virus. Acyclovir inhibits the DNA polymerase of the virus, preventing further proliferation.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D06BB03 | Aciclovir | D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06B Chemotherapeutics for topical use → D06BB Antivirals |
| J05AB01 | Aciclovir | J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors |
| S01AD03 | Aciclovir | S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AD Antivirals |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| Zovirax Eye Ointment | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ZOVIRAX Dispersible film-coated tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ZOVIRAX Cream | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| Zovirax Intravenous injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| SITAVIG Delayed-release tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Aciclovir is an active ingredient of these brands:
Albania (AL)Austria (AT)
Brazil (BR)Ecuador (EC)Estonia (EE)
France (FR)Germany (DE)Hong Kong (HK)
Ireland (IE)
Israel (IL)Japan (JP)Malta (MT)Mexico (MX)Netherlands (NL)
Poland (PL)Singapore (SG)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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