Active Ingredient: Memantine
Treatment of adult patients with moderate to severe Alzheimer’s disease.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 5 milligrams memantine, once daily, over the duration of 7 days. Afterwards, oral, 10 milligrams memantine, once daily, over the duration of 7 days. Afterwards, oral, 15 milligrams memantine, once daily, over the duration of 7 days. Afterwards, oral, 20 milligrams memantine, once daily.
The maximum daily dose is 20 mg per day.
In order to reduce the risk of undesirable effects, the maintenance dose is achieved by upward titration of 5 mg per week over the first 3 weeks as follows.
Week 1 (day 1-7): The patient should take 5 mg per day for 7 days.
Week 2 (day 8-14): The patient should take 10 mg per day for 7 days.
Week 3 (day 15-21): The patient should take 15 mg per day for 7 days.
From Week 4 on: The patient should take 20 mg per day.
The recommended maintenance dose is 20 mg per day.
Should be taken at the same time every day with or without food.
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