Chemical formula: C₁₂H₂₁N Molecular mass: 179.302 g/mol PubChem compound: 4054
Memantine is a voltage-dependent, moderate-affinity uncompetitive NMDA-receptor antagonist. It modulates the effects of pathologically elevated tonic levels of glutamate that may lead to neuronal dysfunction.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N06DX01 | Memantine | N Nervous system → N06 Psychoanaleptics → N06D Anti-dementia drugs → N06DX Other anti-dementia drugs |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| NEMDATINE Film-coated tablets | European Medicines Agency (EU) | MPI, EU: SmPC |
Memantine is an active ingredient of these brands:
United States (US)Austria (AT)Brazil (BR)
Canada (CA)
Croatia (HR)Cyprus (CY)Ecuador (EC)
Estonia (EE)
Finland (FI)Germany (DE)Hong Kong (HK)Ireland (IE)Israel (IL)Italy (IT)Japan (JP)
Lithuania (LT)
Mexico (MX)
New Zealand (NZ)
Poland (PL)
Romania (RO)Singapore (SG)South Africa (ZA)Spain (ES)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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