Herpes simplex virus infection

Active Ingredient: Aciclovir

Indication for Aciclovir

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Aciclovir is indicated for the treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes (excluding neonatal HSV and severe HSV infections in immunocompromised children).

For this indication, competent medicine agencies globally authorize below treatments:

200mg five times daily

Route of admnistration

Oral

Defined daily dose

1,000 mg

Dosage regimen

200 mg 5 time(s) per day every day for 5 day(s)

Detailed description

200 mg aciclovir should be taken five times daily at approximately four hourly intervals omitting the night time dose. Treatment should continue for 5 days, but in severe initial infections this may have to be extended.

5 applications daily

Route of admnistration

Cutaneous

Defined daily dose

5 {spreads}

Dosage regimen

1 {spreads} 5 time(s) per day every day for 5 day(s)

Detailed description

Cream should be applied five times daily at approximately four hourly intervals, omitting the night time application. Treatment should be continued for at least 4 days for herpes labialis and for 5 days for genital herpes. If healing has not occurred then treatment may be continued for up to an additional 5 days.

5 mg/kg body weight every 8 hours

Route of admnistration

Intravenous

Defined daily dose

15 mg per kg of body weight

Dosage regimen

5 mg per kg of body weight 3 time(s) per day every day

Detailed description

Patients with Herpes simplex (except herpes encephalitis) or Varicella zoster infections should be given aciclovir I.V. in doses of 5 mg/kg body weight every 8 hours provided renal function is not impaired.

Active ingredient

Aciclovir

Acyclovir is an antiviral agent with activity against herpes simplex virus and varicella-zoster virus. Acyclovir inhibits the DNA polymerase of the virus, preventing further proliferation.

Read more about Aciclovir

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