Moderate to severe pain

Active Ingredient: Pethidine

Indication for Pethidine

Population group: only adults (18 - 65 years old)

Pethidine hydrochloride may be used as an analgesic for the relief of moderate to severe pain including: obstetric analgesia; pre-operative medication and analgesia during anaesthesia; post-operative analgesia.

For this indication, competent medicine agencies globally authorize below treatments:

50-900 mg in 1-6 divided doses

Route of admnistration

Oral

Defined daily dose

50 - 900 mg

Dosage regimen

From 8.333 To 150 mg 6 time(s) per day every day

Detailed description

The normal single dose, usually not to be repeated more often than four hourly, is as follow: 50-150 mg.

25-600 mg in 1-6 divided doses

Route of admnistration

Intramuscular

Defined daily dose

25 - 600 mg

Dosage regimen

From 4.167 To 100 mg 6 time(s) per day every day

Detailed description

The following single dose may be used and should not usually be repeated more frequently than four hourly: 25-100mg.

25-600 mg in 1-6 divided doses

Route of admnistration

Subcutaneous

Defined daily dose

25 - 600 mg

Dosage regimen

From 4.167 To 100 mg 6 time(s) per day every day

Detailed description

The following single dose may be used and should not usually be repeated more frequently than four hourly: 25-100mg.

25-300 mg in 1-6 divided doses

Route of admnistration

Intravenous

Defined daily dose

25 - 300 mg

Dosage regimen

From 4.167 To 50 mg 6 time(s) per day every day

Detailed description

The following single dose may be used and should not usually be repeated more frequently than four hourly: 25-100mg.

Dosage considerations

Slow intravenous injection.

Active ingredient

Pethidine

Pethidine is a synthetic opioid analgesic similar with similar actions to morphine. Like other opioids, pethidine binds to opioid receptors and exerts its principal pharmacological actions on the central nervous system where its analgesic and sedative effects are of particular therapeutic value. Pethidine also causes the release of histamine from mast cells resulting in a number of allergic-type reactions.

Read more about Pethidine

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