Pethidine Other names: Pethidine Pethidine Hydrochloride

Chemical formula: C₁₅H₂₁NO₂  Molecular mass: 247.333 g/mol  PubChem compound: 4058

Active ingredient description

Pethidine is a synthetic opioid analgesic similar with similar actions to morphine. Like other opioids, pethidine binds to opioid receptors and exerts its principal pharmacological actions on the central nervous system where its analgesic and sedative effects are of particular therapeutic value. Pethidine also causes the release of histamine from mast cells resulting in a number of allergic-type reactions.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02AB02 Pethidine N Nervous system → N02 Analgesics → N02A Opioids → N02AB Phenylpiperidine derivatives
Discover more medicines within N02AB02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PETHIDINE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
PETHIDINE Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 57-42-1
DrugBank Drug: DB00454
KEGG Drug: D08343
PubChem Compound: 4058
RxNorm Ingredient: 6754
SNOMED-CT Concept: 387298007
Pethidine (substance)
UNII Identifier: 9E338QE28F
MEPERIDINE

Medicines

Pethidine is an active ingredient of these brands:

United States (US)

  • DEMEROL as MEPERIDINE HYDROCHLORIDE

Austria (AT)

  • ALODAN as Pethidine hydrochloride

Brazil (BR)

Estonia (EE)

Israel (IL)

Japan (JP)

  • (combination) PETHILORFAN as MEPERIDINE HYDROCHLORIDE

Lithuania (LT)

  • DOLOBLOK as MEPERIDINE HYDROCHLORIDE
  • DOLSIN as MEPERIDINE HYDROCHLORIDE

Malta (MT)

Poland (PL)

Romania (RO)

Spain (ES)

Turkey (TR)

  • ALDINE as MEPERIDINE HYDROCHLORIDE
  • CEDEPTIN as MEPERIDINE HYDROCHLORIDE
  • PETHOLAN as MEPERIDINE HYDROCHLORIDE
  • PETISEL as MEPERIDINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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