Active Ingredient: Dihydrocodeine
For the relief of severe pain in cancer and other chronic conditions.
Dihydrocodeine is indicated for the treatment of opioid-responsive, chronic severe pain of non-malignant origin, after other conservative methods of analgesia have been tried. It is indicated for use in accordance with the current guidelines on chronic pain management and where there is no psychological contraindication, medicine-seeking behaviour or history of medicine misuse.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, between 60 milligrams dihydrocodeine and 120 milligrams dihydrocodeine, once every 12 hours.
Dihydrocodeine should be taken at twelve-hourly intervals at a dose of 60-120 mg twice daily depending on the severity of the patient’s pain. The maximum recommended dose is 240 mg daily since higher doses do not provide any further analgesic effect.
Dihydrocodeine should be administered initially at the lowest dose possible in elderly.
Prior to starting treatment with opioids, a discussion should be held with patients to put in place a strategy for ending treatment with dihydrocodeine in order to minimise the risk of addiction and drug withdrawal syndrome.
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