Dihydrocodeine Other names: Drocode Paracodeine Parzone

Chemical formula: C₁₈H₂₃NO₃  Molecular mass: 301.38 g/mol  PubChem compound: 5284543

Active ingredient description

Dihydrocodeine is a semisynthetic narcotic analgesic with a potency between morphine and codeine. It is also a centrally-acting anti-tussive. Dihydrocodeine works on the cough centre to lessen the incidence and intensity of coughing fits.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02AA08 Dihydrocodeine N Nervous system → N02 Analgesics → N02A Opioids → N02AA Natural opium alkaloids
Discover more medicines within N02AA08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PARACODIN Tablet Health Products Regulatory Authority (IE) MPI, EU: SmPC
PARACODIN Oral drops, solution Health Products Regulatory Authority (IE) MPI, EU: SmPC
PARACODIN Syrup Health Products Regulatory Authority (IE) MPI, EU: SmPC
DHC CONTINUS Tablet Medicines and Medical Devices Safety Authority (NZ) MPI, EU: SmPC
DHC CONTINUS Prolonged release tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 125-28-0
DrugBank Drug: DB01551
KEGG Drug: D01481
PubChem Compound: 5284543
RxNorm Ingredient: 23088
SNOMED-CT Concept: 387322000
Dihydrocodeine (substance)
UNII Identifier: 8LXS95BSA9
DIHYDROCODEINE BITARTRATE
UNII Identifier: N9I9HDB855
DIHYDROCODEINE

Medicines

Dihydrocodeine is an active ingredient of these brands:

United States (US)

  • (combination) DVORAH as DIHYDROCODEINE BITARTRATE
  • (combination) TREZIX as DIHYDROCODEINE BITARTRATE

Austria (AT)

Cyprus (CY)

France (FR)

  • DICODIN as DIHYDROCODEINE BITARTRATE

Germany (DE)

Hong Kong (HK)

  • REUTOO as DIHYDROCODEINE BITARTRATE

  • (combination) CODAEWON as DIHYDROCODEINE BITARTRATE
  • (combination) CODE-C as DIHYDROCODEINE BITARTRATE
  • (combination) CODENAL as DIHYDROCODEINE BITARTRATE
  • (combination) CODENS as DIHYDROCODEINE BITARTRATE
  • (combination) PARACODONE as DIHYDROCODEINE BITARTRATE

Ireland (IE)

Japan (JP)

  • (combination) CHLOPHEDRIN S as DIHYDROCODEINE PHOSPHATE
  • (combination) COUGHCODE-N as DIHYDROCODEINE PHOSPHATE
  • (combination) HUSCODE as DIHYDROCODEINE PHOSPHATE
  • (combination) MUCOBROTIN as DIHYDROCODEINE PHOSPHATE
  • (combination) SEKICODE as DIHYDROCODEINE PHOSPHATE

Malta (MT)

Spain (ES)

United Kingdom (UK)

  • (combination) PARAMOL as DIHYDROCODEINE BITARTRATE
  • (combination) REMEDEINE as DIHYDROCODEINE BITARTRATE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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