Asthma

Active Ingredient: Fluticasone

Indication for Fluticasone

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Fluticasone propionate given by inhalation offers prophylactic treatment for asthma.

Mild asthma: Patients requiring intermittent symptomatic bronchodilator asthma medication on a regular daily basis.

Moderate asthma: Patients with unstable or worsening asthma despite prophylactic therapy or bronchodilator alone.

Severe asthma: Patients with severe chronic asthma and those who are dependent on systemic corticosteroids for adequate control of symptoms. On introduction of inhaled fluticasone propionate many of these patients may be able to reduce significantly, or to eliminate, their requirement for oral corticosteroids.

For this indication, competent medicine agencies globally authorize below treatments:

100-400 micrograms in 2 divided doses daily

Route of admnistration

Respiratory (Inhalation)

Defined daily dose

100 - 400 ug

Dosage regimen

From 50 To 200 ug 2 time(s) per day every day

Detailed description

Typical starting doses for children over 4years of age

50 to 100 micrograms twice daily.

Many children’s asthma will be well controlled using the 50 to 100 microgram twice daily dosing regime. For those patients whose asthma is not sufficiently controlled, additional benefit may be obtained by increasing the dose up to 200 micrograms twice daily.

The maximum licensed dose in children is 200 micrograms twice daily.

The starting dose should be appropriate to the severity of the disease. The dose should be titrated down to the lowest dose at which effective control of asthma is maintained.

Active ingredient

Fluticasone

Fluticasone has anti-inflammatory and vasoconstrictive features. Fluticasone given by inhalation at recommended doses has a potent glucocorticoid anti-inflammatory action within the lungs, resulting in a reduction of both symptoms and exacerbations of asthma, with a lower incidence and severity of adverse effects than those observed when corticosteroids are administered systemically.

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