Chemical formula: C₂₂H₂₇F₃O₄S Molecular mass: 444.51 g/mol
Fluticasone has anti-inflammatory and vasoconstrictive features. Fluticasone given by inhalation at recommended doses has a potent glucocorticoid anti-inflammatory action within the lungs, resulting in a reduction of both symptoms and exacerbations of asthma, with a lower incidence and severity of adverse effects than those observed when corticosteroids are administered systemically.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D07AC17 | Fluticasone | D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AC Corticosteroids, potent (group III) |
| R01AD08 | Fluticasone | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AD Corticosteroids |
| R03BA05 | Fluticasone | R Respiratory system → R03 Drugs for obstructive airway diseases → R03B Other drugs for obstructive airway diseases, inhalants → R03BA Glucocorticoids |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| FLONASE ALLERGY RELIEF Aqueous nasal spray | Health Products and Food Branch (CA) | MPI, CA: SPM | |
| FLIXOTIDE EVOHALER Pressurised inhalation, suspension | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| FLUTICASONE PROPIONATE Cream | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| FLOVENT DISKUS Inhalation powder | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| AVAMYS Nasal spray, suspension | European Medicines Agency (EU) | MPI, EU: SmPC | |
| CUTIVATE Lotion | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Fluticasone is an active ingredient of these brands:
United States (US)
Albania (AL)
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)Italy (IT)
Japan (JP)Lithuania (LT)
Malta (MT)
Mexico (MX)Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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