Active Ingredient: Paliperidone
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, between 6 milligrams paliperidone and 12 milligrams paliperidone, once daily at morning.
The recommended dose of paliperidone for the treatment of schizoaffective disorder in adults is 6 mg once daily, administered in the morning. Initial dose titration is not required. Some patients may benefit from higher doses within the recommended range of 6 mg to 12 mg once daily. Dosage adjustment, if indicated, should occur only after clinical reassessment. When dose increases are indicated, increments of 3 mg/day are recommended and generally should occur at intervals of more than 4 days.
There are no systematically collected data to specifically address switching patients from paliperidone to other antipsychotic medicinal products. Due to different pharmacodynamic and pharmacokinetic profiles among antipsychotic medicinal products, supervision by a clinician is needed when switching to another antipsychotic product is considered medically appropriate.
It should be taken in the morning. It must be swallowed with liquid.
The administration of paliperidone should be standardised in relation to food intake. The patient should be instructed to always take paliperidone in the fasting state or always take it together with breakfast and not to alternate between administration in the fasting state or in the fed state.
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