Chemical formula: C₂₃H₂₇FN₄O₃ Molecular mass: 426.484 g/mol PubChem compound: 115237
Paliperidone is a selective blocking agent of monoamine effects, whose pharmacological properties are different from that of traditional neuroleptics. Even though paliperidone is a strong D2-antagonist, which is believed to relieve the positive symptoms of schizophrenia, it causes less catalepsy and decreases motor functions to a lesser extent than traditional neuroleptics.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N05AX13 | Paliperidone | N Nervous system → N05 Psycholeptics → N05A Antipsychotics → N05AX Other antipsychotics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| XEPLION Prolonged release suspension for injection | European Medicines Agency (EU) | MPI, EU: SmPC | |
| INVEGA Prolonged-release tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Paliperidone is an active ingredient of these brands:
Australia (AU)Brazil (BR)Canada (CA)Croatia (HR)Ecuador (EC)Germany (DE)Ireland (IE)New Zealand (NZ)Nigeria (NG)Poland (PL)Romania (RO)Singapore (SG)South Africa (ZA)Spain (ES)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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