Active Ingredient: Risedronic acid
Treatment of osteoporosis in men at high risk of fractures.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 35 milligrams risedronic acid, once weekly.
The recommended dose in adults is one 35 mg tablet orally once a week. The tablet should be taken on the same day each week.
The absorption of risedronate sodium is affected by food, thus to ensure adequate absorption patients should take risedronate sodium:
Before breakfast: At least 30 minutes before the first food, other medicinal product or drink (other than plain water) of the day.
Patients should be instructed that if a dose is missed, one risedronate sodium 35 mg tablet should be taken on the day that the tablet is remembered. Patients should then return to taking one tablet once a week on the day the tablet is normally taken. Two tablets should not be taken on the same day.
The tablet must be swallowed whole and not sucked or chewed. To aid delivery of the tablet to the stomach risedronate sodium is to be taken while in an upright (standing or sitting) position with a glass of plain water (≥120 ml). Patients should not lie down for 30 minutes after taking the tablet.
Supplemental calcium and vitamin D should be considered, if the dietary intake is inadequate.
The optimal duration of bisphosphonate treatment for osteoporosis has not been established. The need for continued treatment should be re-evaluated periodically based on the benefits and potential risks of risedronate on an individual patient basis, particularly after 5 or more years of use.
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