Risedronic acid Other names: Risedronate sodium

Chemical formula: C₇H₁₁NO₇P₂  Molecular mass: 283.112 g/mol  PubChem compound: 5245

Active ingredient description

Risedronic acid is a pyridinyl bisphosphonate that binds to bone hydroxyapatite and inhibits osteoclast-mediated bone resorption. The bone turnover is reduced while the osteoblast activity and bone mineralisation is preserved.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
M05BA07 Risedronic acid M Musculo-skeletal system → M05 Drugs for treatment of bone diseases → M05B Drugs affecting bone structure and mineralization → M05BA Bisphosphonates
Discover more medicines within M05BA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
RISEDRONATE SODIUM 5 mg Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
RISEDRONATE SODIUM 35 mg Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
RISEDRONATE SODIUM 30 mg Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 105462-24-6
CAS Substance: 115436-72-1
DrugBank Drug: DB00884
KEGG Drug: D08484
PubChem Compound: 5245
RxNorm Ingredient: 55685
SNOMED-CT Concept: 105590001
Substance (substance)
SNOMED-CT Concept: 768539002
Risedronic acid (substance)
UNII Identifier: KM2Z91756Z
RISEDRONIC ACID

Medicines

Risedronic acid is an active ingredient of these brands:

United States (US)

  • ACTONEL as RISEDRONATE SODIUM

  • (combination) ATELVIA as RISEDRONATE SODIUM MONOHYDRATE
  • (combination) ATELVIA as RISEDRONATE SODIUM HEMI-PENTAHYDRATE

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

  • ACTONEL as RISEDRONATE SODIUM
  • BONNA as RISEDRONATE SODIUM
  • RISBON as RISEDRONATE SODIUM HEMI-PENTAHYDRATE

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

  • RIBONE as RISEDRONATE SODIUM

Italy (IT)

Japan (JP)

  • ACTONEL as RISEDRONATE SODIUM
  • BENET as Sodium risedronate hydrate

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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