Type I diabetic nephropathy

Active Ingredient: Captopril

Indication for Captopril

Population group: only elderly (65 years old or older)

Captopril is indicated for the treatment of macroproteinuric diabetic nephropathy in patients with type I diabetes.

For this indication, competent medicine agencies globally authorize below treatments:

6.25-100 mg in 1-2 divided doses daily

Route of admnistration

Oral

Defined daily dose

6.25 - 100 mg

Dosage regimen

From 3.125 To 50 mg 2 time(s) per day every day

Detailed description

As with other antihypertensive agents, consideration should be given to initiating therapy with a lower starting dose (6.25 mg BID) in elderly patients who may have reduced renal function and other organ dysfunctions.

Dosage should be titrated against the blood pressure response and kept as low as possible to achieve adequate control.

Active ingredient

Captopril

Captopril is a highly specific, competitive inhibitor of angiotensin-I converting enzyme (ACE inhibitors). Inhibition of ACE results in decreased plasma angiotensin-II, which leads to decreased vasopressor activity and to reduced aldosterone secretion. In patients with hypertension, captopril causes a reduction in supine and erect blood pressure, without inducing any compensatory increase in heart rate, nor water and sodium retention.

Read more about Captopril

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.