Active Ingredient: Colestilan
Colestilan is indicated for the treatment of hyperphosphataemia in adult patients with Chronic Kidney Disease (CKD) Stage 5 receiving haemodialysis or peritoneal dialysis.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, between 6 grams colestilan and 12 grams colestilan, divided 3 times daily.
The recommended starting dose is 6-9 g per day (2-3 g three times daily).
Patients previously on other phosphate binders who are switched to BindRen should start taking 6-9 g per day (2-3 g three times daily).
Serum phosphorus concentrations should be monitored. If an acceptable serum phosphorus concentration is not achieved, the dose may be increased by 3 g per day (1 g three times daily) in 2-3 weekly intervals. The maximum daily dose of BindRen tested in clinical trials was 15 g per day (5 g three times daily).
The daily dose of should be taken in three equally divided doses with or immediately after meals with a sufficient amount of water to aid swallowing.
The division of the daily dose may be adjusted on a physician’s advice taking into account the dietary intake of phosphate. Patients should be encouraged to adhere to their prescribed low phosphate diets.
Treatment of high blood phosphorus levels usually requires long-term treatment.
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