Colestilan

Chemical formula: C₇H₁₁ClN₂O  Molecular mass: 174.056 g/mol 

Active ingredient description

Colestilan is a non-absorbed, non-calcium, non-metallic phosphate-binding polymer. The binding sites become partially protonated in the stomach and interact through ionic and hydrogen bonding with both dietary phosphate anions and bile acids in the duodenum. By binding phosphate from food in the digestive tract, colestilan lowers the serum phosphorus concentration. Colestilan also binds bile acids, thereby lowering the serum LDL-cholesterol concentration.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V03AE06 V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia
Discover more medicines within V03AE06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
BINDREN Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

External identifiers

CAS Substance: 95522-45-5
DrugBank Drug: DB11634
KEGG Drug: D01934
UNII Identifier: VSI302RYSR
COLESTILAN CHLORIDE

Medicines

Colestilan is an active ingredient of these brands:

Estonia (EE)

Japan (JP)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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