Chemical formula: C₇H₁₁ClN₂O Molecular mass: 174.056 g/mol
Colestilan is a non-absorbed, non-calcium, non-metallic phosphate-binding polymer. The binding sites become partially protonated in the stomach and interact through ionic and hydrogen bonding with both dietary phosphate anions and bile acids in the duodenum. By binding phosphate from food in the digestive tract, colestilan lowers the serum phosphorus concentration. Colestilan also binds bile acids, thereby lowering the serum LDL-cholesterol concentration.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code | Group title | Classification |
---|---|---|
V03AE06 | V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title | Information Source | Document Type | |
---|---|---|---|
BINDREN Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Colestilan is an active ingredient of these brands:
Estonia (EE)Japan (JP)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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