Active Ingredient: Neostigmine
Reversal of neuromuscular blockade with neostigmine should not be attempted unless there is spontaneous recovery from paralysis.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intravenous, between 0.05 milligrams neostigmine per kilogram of body weight and 0.07 milligrams neostigmine per kilogram of body weight, one dose.
2.5 mg neostigmine (maximum per dose 5 mg), to be given over 1 minute, after or with glycopyrronium or atropine. Repeat if necessary.
For:
Intravenous, between 0.05 milligrams neostigmine per kilogram of body weight and 0.07 milligrams neostigmine per kilogram of body weight, one dose.
50 micrograms neostigmine per kg bodyweight (maximum per dose 2.5 mg neostigmine methylsulfate) to be given over 1 minute after or with glycopyrronium or atropine, followed by a further dose of 25 micrograms/kg neostigmine if required.
For:
Intravenous, 0.05 milligrams neostigmine per kilogram of body weight, one dose.
50 micrograms neostigmine per kg bodyweight to be given over 1 minute after or with glycopyrronium or atropine, followed by a further dose of 25 micrograms/kg neostigmine if required.
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