Chemical formula: C₁₂H₁₉N₂O₂⁺ Molecular mass: 223.292 g/mol PubChem compound: 4456
Neostigmine inhibits cholinesterase activity and prolongs and intensifies the muscarinic and nicotinic effects of acetylcholine. The anticholinesterase actions of neostigmine are reversible. It is used mainly for its action on skeletal muscle and less frequently to increase the activity of smooth muscle.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N07AA01 | Neostigmine | N Nervous system → N07 Other nervous system drugs → N07A Parasympathomimetics → N07AA Anticholinesterases |
| S01EB06 | Neostigmine | S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EB Parasympathomimetics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| NEOSTIGMINE Sterile injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| NEOSTIGMINE BROMIDE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Neostigmine is an active ingredient of these brands:
United States (US)
Austria (AT)Brazil (BR)
Croatia (HR)
Estonia (EE)
Finland (FI)
France (FR)
Ireland (IE)
Japan (JP)
Lithuania (LT)
Mexico (MX)
Netherlands (NL)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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