Moderate to severe pain, postoperative pain

Active Ingredient: Nalbuphine

Indication for Nalbuphine

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Nalbuphine is indicated for the short-term relief of moderate to severe pain. It can also be used for pre- and post-operative analgesia.

For this indication, competent medicine agencies globally authorize below treatments:

0.4-0.8 mg/kg in 4 divided doses daily

Route of admnistration

Subcutaneous

Defined daily dose

0.4 - 0.8 mg per kg of body weight

Dosage regimen

From 0.1 To 0.2 mg per kg of body weight 4 time(s) per day every day

Detailed description

The usual recommended dose for children is 0.1-0.2 mg/kg body weight. This dose may be administered intravenously, intramuscularly or subcutaneously. Intramuscular as well as subcutaneous administration might be painful and should be avoided in children.

The dose may be repeated after 3 to 6 hours, if necessary. The single maximum dose is fixed with 0.2 mg nalbuphine hydrochloride per kilogram body weight.

There are no adequate data for the treatment of children younger than 1.5 years.

0.4-0.8 mg/kg in 4 divided doses daily

Route of admnistration

Intramuscular

Defined daily dose

0.4 - 0.8 mg per kg of body weight

Dosage regimen

From 0.1 To 0.2 mg per kg of body weight 4 time(s) per day every day

Detailed description

The usual recommended dose for children is 0.1-0.2 mg/kg body weight. This dose may be administered intravenously, intramuscularly or subcutaneously. Intramuscular as well as subcutaneous administration might be painful and should be avoided in children.

The dose may be repeated after 3 to 6 hours, if necessary. The single maximum dose is fixed with 0.2 mg nalbuphine hydrochloride per kilogram body weight.

There are no adequate data for the treatment of children younger than 1.5 years.

0.4-0.8 mg/kg in 4 divided doses daily

Route of admnistration

Intravenous

Defined daily dose

0.4 - 0.8 mg per kg of body weight

Dosage regimen

From 0.1 To 0.2 mg per kg of body weight 4 time(s) per day every day

Detailed description

The usual recommended dose for children is 0.1-0.2 mg/kg body weight. This dose may be administered intravenously, intramuscularly or subcutaneously. Intramuscular as well as subcutaneous administration might be painful and should be avoided in children.

The dose may be repeated after 3 to 6 hours, if necessary. The single maximum dose is fixed with 0.2 mg nalbuphine hydrochloride per kilogram body weight.

There are no adequate data for the treatment of children younger than 1.5 years.

Active ingredient

Nalbuphine

Nalbuphine is an opioid with kappa-agonistic and mu-antagonistic properties. Beside the essential agonistic (analgesic) effect nalbuphine has antagonistic effects of about a fourth of nalorfine and ten times of pentazocine.

Read more about Nalbuphine

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