Chemical formula: C₂₁H₂₇NO₄ Molecular mass: 357.443 g/mol PubChem compound: 5311304
Nalbuphine is an opioid with kappa-agonistic and mu-antagonistic properties. Beside the essential agonistic (analgesic) effect nalbuphine has antagonistic effects of about a fourth of nalorfine and ten times of pentazocine.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N02AF02 | Nalbuphine | N Nervous system → N02 Analgesics → N02A Opioids → N02AF Morphinan derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| NALPAIN Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| NUBAIN Solution for injection | Health Products and Food Branch (CA) | MPI, CA: SPM |
Nalbuphine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Canada (CA)
Estonia (EE)
France (FR)
Hong Kong (HK)
Ireland (IE)
Poland (PL)
South Africa (ZA)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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