Active Ingredient: Captopril
Captopril is indicated for the treatment of chronic heart failure.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
6.25 - 150 mg
From 3.125 To 75 mg 2 time(s) per day every day
Treatment with captopril for heart failure should be initiated under close medical supervision. The usual starting dose is 6.25 mg-12.5 mg BID or TID. Titration to the maintenance dose (75-150 mg per day) should be carried out based on patient’s response, clinical status and tolerability, up to a maximum of 150 mg per day in divided doses. The dose should be increased incrementally, with intervals of at least 2 weeks to evaluate patient’s response.
As with other antihypertensive agents, consideration should be given to initiating therapy with a lower starting dose (6.25 mg BID) in elderly patients who may have reduced renal function and other organ dysfunctions.
Dosage should be titrated against the blood pressure response and kept as low as possible to achieve adequate control.
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