Active Ingredient: Bleomycin
For this indication, competent medicine agencies globally authorize below treatments:
Intrapleural
60,000 - 60,000 [iU]
From 60,000 To 60,000 [iU] once every 28 day(s)
60 × 103 IU in 100 mL physiological saline solution intrapleurally, as a single dose, which can be repeated after 2-4 weeks, depending on the response. Since approximately 45% of bleomycin is absorbed, this should be taken into account for the lifetime cumulative dose (body surface area, kidney function and lung function).
Following drainage of the pleural cavity, bleomycin, dissolved in 100 ml physiological saline solution, is instilled via the puncture cannula or drainage catheter. The cannula or catheter is then removed. In order to ensure uniform distribution of the bleomycin in the serous cavity, the position of the patient should be changed every 5 minutes for a period of 20 minutes. Approximately 45% of Bleomycin will be absorbed; this has to be considered for the total dose (body surface area, kidney function, lung function).
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