Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2018 Publisher: Accord Healthcare Limited, Sage House, 319, Pinner Road, North Harrow, Middlesex HA1 4HF, United Kingdom
Bleomycin 15000 IU Powder for solution for injection/infusion.
| Pharmaceutical Form |
|---|
|
Powder for solution for injection/infusion. White to light yellowish freeze dried substance. pH: Between 4.5 to 6.0 Osmlolarity: 260 to 340 mOsm/ltr |
Each vial contains 15000 intenational units (I.U) of bleomycin (as bleomycin sulphate).
Excipient with known effect: Each vial contains <1 mmol sodium.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Bleomycin |
Bleomycin is a mixture of basic, water-soluble glycopeptide-antibiotics with cytotoxic activity. Bleomycin acts by interacting with both single and double-stranded DNA (deoxyribonucleic acid) leading to both single and double-strand scission, which leads in turn to inhibition of cell division, inhibition of growth and inhibition of DNA synthesis. Bleomycin can also influence RNA (ribonucleic acid) and protein biosynthesis to a lesser extent. |
| List of Excipients |
|---|
|
Sodium hydroxide (for pH adjustment) |
6 ml Type I tubular clear glass vial, closed with bromobutyl rubber stopper and sealed with a flip-off aluminium seal.
Availbale in pack of 1vial. 10 and 100 vials.
Not all pack sizes may be marketed.
Accord Healthcare Limited, Sage House, 319, Pinner Road, North Harrow, Middlesex HA1 4HF, United Kingdom
PL 20075/0440
Date of first authorisation: 08th July 2016
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
