Source: FDA, National Drug Code (US) Revision Year: 2020
GLUCOTROL (glipizide) is an oral blood-glucose-lowering drug of the sulfonylurea class.
The Chemical Abstracts name of glipizide is 1-cyclohexyl-3-[[p-[2-(5-methylpyrazine-carboxamido)ethyl]phenyl]sulfonyl]urea. The molecular formula is C21H27N5O4S; the molecular weight is 445.55; the structural formula is shown below:
Glipizide is a whitish, odorless powder with a pKa of 5.9. It is insoluble in water and alcohols, but soluble in 0.1 N NaOH; it is freely soluble in dimethylformamide. GLUCOTROL tablets for oral use are available in 5 and 10 mg strengths.
Inert ingredients are: colloidal silicon dioxide; lactose; microcrystalline cellulose; starch; stearic acid.
| How Supplied | ||||
|---|---|---|---|---|
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GLUCOTROL tablets are white, dye-free, scored, diamond-shaped, and imprinted as follows: 5 mg–Pfizer 411; 10 mg–Pfizer 412.
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| Drug | Countries | |
|---|---|---|
| GLUCOTROL | Estonia, Hong Kong, Lithuania, Romania, Turkey, United States |
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