Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2011 Publisher: Sandoz Ltd Frimley Business Park Frimley Camberley Surrey GU16 7SR United Kingdom
Carbo-Dome Cream contains coal tar an antipruritic and keratoplastic. Its used in the treatment eczema, psoriasis and other skin conditions. Tar acids have also been shown to have disinfectant properties. Carbo-Dome Cream may be used on its own or as part of a more extensive treatment regimen.
The product is designed for external use only. Absorption of the coal tar is not reported in ‘Martindale’ and therefore the pharmacokinetics is not addressed.
In animal studies on coal tar has an increase in incidence of epidermal carcinomas and self-limiting keratoacanthomas.
While the ingredients of coal tar have been shown to express genotoxic properties, epidemiological studies with patients have been shown to be inconclusive concerning the potential carcinogenic risks of coal tar products in long term treatment. Nevertheless the possible risk of prolonged treatment should be taken into account when using this product.
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