ART Capsule Ref.[8253] Active ingredients: Diacerein

Publisher: Rafa Laboratories Ltd, POB 405, Jerusalem 91003

Therapeutic indications

Symptomatic treatment of functional symptoms and signs of osteoarthritis.

Note: action onset is deferred: a period of 30 to 45 days precedes analgesic effect onset. Treatment may therefore have to be initiated with standard immediate action onset analgesics/anti-inflammatories.

Posology and method of administration

ADULTS (aged over 15 years).

Oral route.

The capsules should be swallowed whole, without chewing, with a glass of water, preferably during a meal.

The recommended dosage is 2 capsules daily, 1 in the morning, 1 in the evening.

In elderly subjects or those suffering from moderate liver or kidney failure, there is no need to adjust the dosage.

In patients suffering from severe kidney failure (creatinine clearance less than 30ml/min), the daily dosage should be halved.

Overdose

Profuse diarrhoea may occur in the event of overdose. Symptomatic treatment should then be instituted and electrolyte disorders and dehydration corrected if necessary.

Shelf life

3 years.

Special precautions for storage

Store at room temperature.

Nature and contents of container

30 capsules in heat-formed blister packs (PVC/aluminium).

Special precautions for disposal and other handling

Not applicable.

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