Source: Health Products Regulatory Authority (ZA) Revision Year: 2022 Publisher: Douglas Pharmaceuticals Ltd, P O Box 45 027, Auckland 0651, New Zealand Phone: (09) 835 0660
Azamun 25 mg, 50 mg, 75 mg, 100mg, Film coated tablet.
| Pharmaceutical Form |
|---|
|
Azamun 25 mg: Light yellow, circular, biconvex tablet engraved “AZA” and “25” on one side and plain on the other side. Azamun 50 mg: Light yellow, circular, biconvex tablet engraved “AZA”' break-line “50” on one side and plain on the other side. Azamun 75 mg: Light yellow, circular, biconvex tablet engraved “AZA” and “75” on one side and plain on the other side. Azamun 100 mg: Light yellow, circular, biconvex tablet engraved “AZA” and “100” on one side and plain on the other side. The scoreline on Azamun 50 mg is not intended for breaking the tablet. |
Azamun 25 mg: each tablet contains 25 mg azathioprine.
Azamun 50 mg: each tablet contains 50 mg azathioprine.
Azamun 75 mg: each tablet contains 75 mg azathioprine.
Azamun 100 mg: each tablet contains 100 mg azathioprine.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Azathioprine |
Azathioprine is a pro-drug of 6-mercaptopurine (6-MP). 6-MP is inactive but acts as a purine antagonist and requires cellular uptake and intracellular anabolism to thioguanine nucleotides (TGNs) for immunosuppression. The TGNs and other metabolites (e.g. 6-methyl-mecaptopurine ribonucleotides) inhibit de novo purine synthesis and purine nucleotide interconversions. |
| List of Excipients |
|---|
|
Azamun contains cellulose microcrystalline, mannitol, povidone, maize starch, croscarmellose sodium, sodium stearyl fumarate in the tablet core. The tablet coating contains Opadry clear OY7240 (macrogol 400 and hypromellose). |
Azamun 25 mg: 30, 60 and 100 tablets in PVC/PVDC-Aluminium foil blister strips.
Azamun 50 mg, 75 mg, 100 mg: 100 tablets in PVC/PVDC-Aluminium foil blister strips.
Not all strengths or pack sizes may be marketed.
Douglas Pharmaceuticals Ltd, P O Box 45 027, Auckland 0651, New Zealand
Phone: (09) 835 0660
Date of first approval:
Azamun 50 mg: 13 August 1998
Azamun 25 mg, 75 mg, 100 mg: 26 June 2014
| Drug | Countries | |
|---|---|---|
| AZAMUN | Hong Kong, New Zealand, South Africa |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
