Source: Υπουργείο Υγείας (CY) Revision Year: 2019 Publisher: Codal Synto Ltd, 21 Constantinoupoleos, 3011 Limassol, Cyprus
Pharmacotherapeutic group: antivertigo preparations
ATC code: N07CA01
The active ingredient is a specific histamine agonist with virtually no H2-activity. It appears to act on the precapillary sphincter in the stria vascularis of the inner ear, thus reducing the pressure in the endolymphatic space.
Betahistine is rapidly and completely absorbed after oral administration of the drug in tablets. It is excreted almost quantitatively in urine as 2-pyridylacetic acid within 24 hours after administration. No unchanged betahistine has been detected.
There are no preclinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.
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