Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2022 Publisher: AstraZeneca UK Limited, 1 Francis Crick Avenue, Cambridge, CB2 0AA, UK
For bronchodilation: Terbutaline is a selective beta2-adrenergic agonist recommended for the relief and prevention of bronchospasm in bronchial asthma and other bronchopulmonary disorders in which bronchospasm is a complicating factor.
When used as maintenance therapy the patient should also receive optimal anti-inflammatory therapy, e.g. inhaled corticosteroids, leukotriene receptor antagonists.
Bricanyl Tablets have a duration of action of 7 to 8 hours. The minimum recommended dosage interval is therefore 7 hours.
During the first 1-2 weeks, 2.5mg (half a tablet) 3 times in a 24-hour period is recommended. The dose may then be increased to 5mg (1 tablet) 3 times in a 24-hour period to achieve adequate bronchodilation.
Dosage as for Adults.
The starting dose should normally be 2.5mg (half a tablet) 2 times in 24 hours. However, in some patients, the dose may need to be increased to 2.5mg 3 times in 24 hours.
For oral use.
Headache, anxiety, tremor, nausea, tonic cramp, palpitations, tachycardia, arrhythmia. A fall in blood pressure sometimes occurs.
Laboratory findings: hypokalaemia, hyperglycaemia and lactic acidosis sometimes occur.
Reduce the dose.
Gastric lavage, administration of activated charcoal. Determination of acid-base balance, blood sugar and electrolytes, particularly serum potassium levels. Monitoring of the heart rate and rhythm and blood pressure. Metabolic changes should be corrected. A cardioselective β-blocker (e.g. metoprolol) is recommended for the treatment of arrhythmias causing haemodynamic deterioration. The β-blocker should be used with care because of the possibility of inducing bronchoconstriction: use with caution in patients with a history of bronchospasm. If the beta2-mediated reduction in the peripheral vascular resistance significantly contributes to the fall in blood pressure, a volume expander should be given.
36 months.
Do not store above 25°C.
Glass bottles and Securitainers of 100 and 500 tablets.
Not all pack sizes may be marketed.
No special requirements for disposal.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
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