Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2017 Publisher: Beacon Pharmaceuticals Ltd, DCC Vital, Westminster Industrial Estate, Repton Road, Measham, DE12 7DT, England
Emergency treatment of acute oral poisoning or drug overdose. Carbomix adsorbs toxic substances and reduces or prevents systematic absorption. The shorter the time interval between ingestion of the toxicant and the administration of Carbomix, the greater is the benefit for the patient. However, as the absorption of massive drug overdoses is often retarded in acute conditions of intoxication, even the delayed administration of Carbomix may be beneficial. In severe intoxication, repeated administration of Carbomix is recommended to prevent absorbed drug being released (in an unbound state) in the lower intestinal tract or to expedite the elimination and prevent the re-absorption of any drug undergoing enterohepatic circulation.
Carbomix granules should be mixed with water and swallowed as a suspension under medical supervision.
50g activated charcoal (one standard treatment pack), repeated if necessary.
25g activated charcoal (half the contents of the standard pack, repeated if necessary.
If a large quantity of toxicant has been ingested, and where there is a risk to life, a dose of 50g is recommended.
Carbomix should be given as soon as possible after the ingestion of the potential poison.
The contents of the bottle are made up to the red band with water and shaken thoroughly.
The suspension is then taken orally or given by intragastric tube using the applicator provided. Carbomix may be administered after emesis or gastric lavage and may be used concurrently with parenteral antidotes such as acetylcystine.
When ipecac syrup is used to induce emesis, it is recommended that Carbomix be administered only after vomiting has been induced and completed, since ipecac syrup is adsorbed by the charcoal thus preventing emesis.
Not applicable. In theory severe constipation would result from excessive use and this could be treated with laxatives.
Unopened: 5 years.
After reconstitution: 24 hours.
Store below 25°C.
Keep container tightly closed.
HDPE bottle and cap containing 50g of activated charcoal (in 61.5g of granules).
For instructions on reconstitution and use, see section 4.2.
Product description after reconstitution: black suspension.
Any unused product or waste material should be disposed of in accordance with local requirements.
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