Source: Health Products Regulatory Authority (IE) Revision Year: 2020 Publisher: Rowa Pharmaceuticals Limited, Newtown, Bantry, Co. Cork, Ireland
Carbosan 2% w/w Gel.
| Pharmaceutical Form |
|---|
|
Gel. A translucent, colourless gel with a lemon odour. |
Each 5 g of Carbosan Gel contains 100 mg carbenoxolone sodium.
Excipient(s) with known effect:
0.60% w/w parahydroxybenzoic acid esters, sodium salt
0.10% w/w lemon oil containing limonene in a range of 0.056 % w/w – 0.078% w/w
16.50% w/w polyoxyethylene 30 cetylstearyl alcohol
For the full list of excipients, see section 6.1
| Active Ingredient | Description | |
|---|---|---|
| Carbenoxolone |
Carbenoxolone is a glycyrrhetinic acid derivative with a steroid-like structure, similar to substances found in the flavor-ful root of the licorice plant. It influences endogenous glucocorticoids by potently inhibiting 11β-hydroxysteroid dehydrogenase. Electrolyte imbalance is a serious side effect of carbenoxolone when used systemically. Carbenoxolone is best known in cellular physiology as a modestly potent, reasonably effective, water-soluble blocker of gap junctions. It exerts anti-inflammatory activity. Carbenoxolone has used orally in the clinical treatment of peptic ulcers, now it is used topically for the treatment of lip sores and mouth ulcers. |
| List of Excipients |
|---|
|
Polyoxyethylene-30-cetylstearyl alcohol |
The immediate container for Carbosan Gel is an aluminium tube that has an external white lacquer and a gold coloured internal lacquer coating. The tube has a white screw-on cap.
Pack size: 5g.
Rowa Pharmaceuticals Limited, Newtown, Bantry, Co. Cork, Ireland
PA0074/011/001
Date of first authorisation: 13 March 1987
Date of last renewal: 13 March 2007
| Drug | Countries | |
|---|---|---|
| CARBOSAN | Ireland, Malta |
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