CLINDOXYL Gel Ref.[50617] Active ingredients: Benzoyl peroxide Clindamycin

Source: Health Products Regulatory Authority (ZA)  Revision Year: 2013  Publisher: GlaxoSmithKline South Africa (Pty) Ltd, 39 Hawkins Avenue, Epping Industria 1, 7460

Product name and form

CLINDOXYL Gel.

Pharmaceutical Form

Gel.

A white to slightly yellow homogenous gel.

Qualitative and quantitative composition

Each 100 g contains: Clindamycin phosphate equivalent to clindamycin 1,00 g and hydrous benzoyl peroxide equivalent to anhydrous benzoyl peroxide 5,00 g.

Active Ingredient Description
Benzoyl peroxide

Benzoyl peroxide is a highly lipophilic, oxidising agent with keratolytic and bacteriocidal effects. The effectiveness of benzoyl peroxide in the treatment of acne vulgaris is primarily attributable to its antibacterial activity, especially with respect to Propionibacterium acnes. Benzoyl peroxide is also believed to be effective in the treatment of acne on account of its anti-inflammatory and mild keratolytic properties.

Clindamycin

Clindamycin is a lincosamide antibiotic with a primarily bacteriostatic action against Gram-positive aerobes and a wide range of anaerobic bacteria. Lincosamides such as clindamycin bind to the 50S subunit of the bacterial ribosome and inhibit the early stages of protein synthesis.

List of Excipients

Pack sizes and marketing

Membrane-sealed aluminium tubes fitted with a white polyethylene screw cap containing 25 g of gel presented in a carton.

Marketing authorization holder

GlaxoSmithKline South Africa (Pty) Ltd, 39 Hawkins Avenue, Epping Industria 1, 7460

Marketing authorization dates and numbers

42/13.11/0441

Drugs

Drug Countries
CLINDOXYL Brazil, Canada, Finland, Singapore, Turkey, South Africa

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