Source: Health Products Regulatory Authority (IE) Revision Year: 2022 Publisher: Clonmel Healthcare Ltd, Waterford Road, Clonmel, Co. Tipperary, E91 D768, Ireland
Co‐Tipol 500 mg/30 mg suppositories.
| Pharmaceutical Form |
|---|
|
Suppository. White to ivory coloured, torpedo shaped suppository. |
Each suppository contains 500mg paracetamol and 30mg codeine phosphate hemihydrate.
Excipient with known effect: contains 12.5 mg of soya lecithin per suppository.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Codeine |
Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain. |
|
| Codeine and Paracetamol |
The combination of paracetamol with codeine is a well-tolerated and effective analgesic. It consists of complementary active substances with different properties, but with common indication, the relief of pain. A special feature of the combination of paracetamol and codeine is the rapid onset of action after 10-20 minutes and the duration of action for 4-6 hours. |
|
| Paracetamol |
Paracetamol is a medication used to treat pain and fever. It does appear to selectively inhibit COX activities in the brain, which may contribute to its ability to treat fever and pain. |
| List of Excipients |
|---|
|
Hard fat |
Aluminium/PE blister strips containing 5 suppositories.
Pack sizes: 10, 25, 50 and hospital pack sizes of 100.
Not all pack sizes may be marketed.
Clonmel Healthcare Ltd, Waterford Road, Clonmel, Co. Tipperary, E91 D768, Ireland
PA0126/332/002
Date of first authorisation: 29th November 2013
Date of last authorisation: 28th November 2018
| Drug | Countries | |
|---|---|---|
| CO-TIPOL | Ireland |
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