Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2018 Publisher: Amdipharm UK Limited, Capital House, 85 King William Street, London EC4N 7BL, UK
Treatment of Addisonian pernicious anaemia.
Prophylaxis and treatment of other macrocytic anaemias due to vitamin B12 deficiency.
Treatment of tobacco amblyopia.
Treatment of Leber’s atrophy.
The following dosages are suitable for children and adults.
Addisonian pernicious anaemia and other macrocytic anaemias without neurological involvement:
Initially: 250 micrograms to 1000 micrograms intramuscularly on alternate days for one or two weeks then 250 micrograms weekly until blood count is normal.
Maintenance: 1000 micrograms every two or three months.
Addisonian pernicious anaemia and other macrocytic anaemias with neurological involvement:
Initially: 1000 micrograms on alternate days as long as improvement continues.
Maintenance: 1000 micrograms every two months.
Prophylaxis of macrocytic anaemias associated with vitamin B12 deficiency resulting from gastrectomy, ileal resection, certain ma/absorption states and vegetarianism:
1000 micrograms every two or three months.
Tobacco amblyopia and Leber’s optic atrophy:
Initially: 1000 micrograms daily by intramuscular injection for two weeks then twice weekly as long as improvement is maintained.
Maintenance: 1000 micrograms every three months or as required.
Treatment is unlikely to be needed in case of overdose.
Shelf life: 36 months.
Protect from light. Store below 25°C.
This medicine is supplied in clear 1ml Type I glass ampoules in cartons of 5 or 10.
None stated.
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.