Source: Marketing Authorisation Holder Revision Year: 2022 Publisher: Oethmaan Biosims (PTY) Ltd, Office 207A, Sherwood House, Greenacres Office Park, c/o Victory and Rustenburg Roads, Victory Park, Johannesburg 2195
COGESIC (Tablets).
| Pharmaceutical Form |
|---|
|
Flat blue tablet, scored on the one side. |
Each tablet contains:
Codeine phosphate 8 mg
Paracetamol 500 mg
Preservative:
Sodium metabisulphite 0,081% m/m
Contains sugar (sucrose) 20 mg
| Active Ingredient | Description | |
|---|---|---|
| Codeine |
Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain. |
|
| Paracetamol |
Paracetamol is a medication used to treat pain and fever. It does appear to selectively inhibit COX activities in the brain, which may contribute to its ability to treat fever and pain. |
| List of Excipients |
|---|
|
Gelatin |
Cartons containing 2 × 10 tablets in push through blister packs.
White plastic (LOPE) Ziploc bag (Patient Ready Pack) containing 56 tablets.
Amber plastic (PVC) bottles containing 100, 500, and 1000 tablets.
White plastic (HOPE) bottles containing 1000 tablets.
Blue/green plastic buckets containing 5000 tablets.
Oethmaan Biosims (PTY) Ltd, Office 207A, Sherwood House, Greenacres Office Park, c/o Victory and Rustenburg Roads, Victory Park, Johannesburg 2195
0/2.8/109
Date of registration: 23 August 1989
| Drug | Countries | |
|---|---|---|
| COGESIC | South Africa |
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