Source: FDA, National Drug Code (US) Revision Year: 2019
While the precise mode of action of dimenhydrinate is not known, it has a depressant action on hyperstimulated labyrinthine function.
Mutagenicity screening tests performed with dimenhydrinate, diphenhydramine, and 8-chlorotheophylline produced positive results in the bacterial systems and negative results in the mammalian systems. There are no human data that indicate dimenhydrinate is a carcinogen or mutagen or that it impairs fertility.
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