Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2019 Publisher: Accord-UK Ltd (Trading style: Accord), Whiddon Valley, Barnstaple, Devon, EX32 8NS
Folic acid is a component of the B group of vitamins and is necessary for the normal production and maturation of red blood cells.
In folate deficient megaloblastic anaemia: 5mg daily for 4 months; up to 15mg daily may be necessary for malabsorption states.
In drug induced folate deficiency: 5mg daily for 4 months; up to 15mg daily may be necessary for malabsorption states.
For prophylaxis in chronic haemolytic states or in renal dialysis: 5mg every 1-7 days depending on underlying disease.
Prevention of neural tube defects in women known to be at risk: 5mg daily started before conception and continued throughout the first trimester.
In established folate deficiency: 5mg daily continued to term.
For young children a more suitable dosage form should be used.
In folate deficient megaloblastic anaemia:
Child 1-18 years 5mg daily for 4 months; maintenance 5mg every 1-7 days.
In haemolytic anaemia; metabolic disorders:
Child 1-12 years 2.5mg-5mg once daily.
Child 12-18 years 5-10mg once daily.
Prophylaxis of folate deficiency in renal dialysis:
Child 1-12 years 250 microgram/kg (max 10mg) once daily.
Children 12-18 years 5-10mg once daily.
For oral administration.
No special procedures or antidote are likely to be needed.
Shelf life: Two years from the date of manufacture.
Shelf-life after dilution/reconstitution: Not applicable.
Shelf-life after first opening: Not applicable.
Store below 25°C in a dry place.
Protect from light.
The product containers are rigid injection moulded polypropylene or injection blow-moulded polyethylene containers and snap-on polyethylene lids; in case any supply difficulties should arise the alternative is amber glass containers with screw caps.
The product may also be supplied in blister packs and cartons:
Blister pack sizes: 7s, 10s, 14s, 21s, 28s, 30s, 56s, 60s, 84s, 90s, 100s, 112s, 500s, 1000s
Securitainers pack sizes: 7s, 10s, 14s, 21s, 28s, 30s, 56s, 60s, 84s, 90s, 100s, 112s, 500s, 1000s
Product may also be supplied in bulk, for reassembly purposes only, in polybags contained in tins, skillets or polybuckets filled with suitable cushioning material.
Maximum size of bulk packs: 150,000.
Not applicable.
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