Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2017 Publisher: Bausch & Lomb UK Limited, Bausch & Lomb House, 106 London Road, Kingston-upon-Thames, Surrey, UK, KT2 6TN
Pharmacotherapeutic group: Artificial tears and other indifferent preparations
ATC code: S01XA20
GelTears contains Carbomer 980, a hydrophilic, high molecular weight polymer of carboxyvinylic acid. The gel forms a transparent lubricating and moistening film on the surface of the eye. The preparation has a pH similar to that found in the normal tear film and is slightly hypotonic with respect to tears. GelTears relieves the symptoms of irritation linked with dry eye syndromes and protects the cornea against drying out.
The use of vital stains has provided objective evidence that the corneal and conjunctival epithelial lesions associated with dry eye syndromes show improvement on treatment with GelTears. The gel remains on the surface of the eye for longer than low viscosity artificial tears and hence, less frequent application is required.
No human pharmacokinetic studies are available, however, absorption or accumulation in ocular tissues is likely to be negligible due to the high molecular weight of the active ingredient.
No adverse safety issues were detected during the development of this formulation. The ingredients are well established in clinical ophthalmology.
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